HitPredict

Interactor 1: VATG2 (O95670)
V-type proton ATPase subunit G 2 (V-ATPase subunit G 2) (V-ATPase 13 kDa subunit 2) (Vacuolar proton pump subunit G 2)
Gene: ATP6V1G2

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	V-ATPase_G~V_ATPase_I
Common GO terms	GO:0016241 - regulation of macroautophagy GO:0046961 - proton-transporting ATPase activity, rotational mechanism
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 856
+	Mm
		1321784 VATG1_MOUSE (1-118): 5.17e-33: 113: 64.41		VPP1_MOUSE (1-842): 0: 1295: 52.83
+	Mm
		1376699 VATG2_MOUSE (1-117): 3.14e-30: 106: 95.73		VPP1_MOUSE (1-842): 0: 1295: 52.83
+	Hs
		260090 VATG1_HUMAN (1-118): 1.67e-31: 109: 63.56		VPP1_HUMAN (1-842): 0: 1278: 53.19
+	Hs
		318296 VATG2_HUMAN (1-118): 1.31e-30: 107: 100.00		VPP1_HUMAN (1-842): 0: 1278: 53.19
+	Hs
		318284 VATG2_HUMAN (1-118): 1.31e-30: 107: 100.00		VPP3_HUMAN (1-843): 0: 1082: 49.35
+	Sc
		693224 VATG_YEAST (3-113): 3.05e-23: 88.3: 32.43		VPP1_YEAST (3-842): 0: 1037: 36.46
+	Sc
		741308 VATG_YEAST (3-113): 3.05e-23: 88.3: 32.43		VPP2_YEAST (3-845): 0: 947: 33.19