HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras, Arm_3~Ras
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 696 Hs			1 538
+	Hs
		911198 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00
+	Hs
		910832 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36
+	Hs
		227267 SPOP_HUMAN (300-648): 4.67e-73: 242: 15.32		IMA7_HUMAN (1-538): 1.96e-160: 469: 80.48
+	At
		198786 BPM3_ARATH (301-668): 9.82e-72: 240: 14.25		IMPA1_ARATH (4-538): 2.11e-160: 468: 52.78
+	Hs
		253606 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		IMA7_HUMAN (1-538): 1.96e-160: 469: 80.48
+	Mm
		204695 SPOP_MOUSE (300-648): 4.67e-73: 242: 15.32		IMA3_MOUSE (1-538): 2.06e-156: 458: 45.47
+	Hs
		227441 SPOP_HUMAN (300-648): 4.67e-73: 242: 15.32		IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00
+	Hs
		142521 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		IMA3_HUMAN (1-538): 2.06e-156: 458: 45.84
+	Hs
		911206 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00
+	Hs
		179009 SPOP_HUMAN (300-648): 4.67e-73: 242: 15.32		IMA6_HUMAN (1-538): 3.86e-153: 450: 79.59
+	Hs
		580943 RAC2_HUMAN (12-219): 4.13e-71: 231: 36.97		IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00
+	Hs
		911200 RHOA_HUMAN (16-215): 2.03e-68: 224: 36.45		IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00
+	Hs
		910846 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36