HitPredict

Interactor 1: SNP29 (O95721)
Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29)
Gene: SNAP29

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.698

Property	Details
Experiments	33961781, 32296183, 35271311, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0031201 - SNARE complex and 1 others more... GO:0061025 - membrane fusion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 100
+	Hs
		320265 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		VAMP1_HUMAN (8-87): 1.27e-25: 93.9: 80.00
+	Hs
		261624 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00
+	Hs
		320281 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		320300 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		320402 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		263128 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Mm
		926350 SNP29_MOUSE (1-258): 2.07e-81: 246: 83.08		VAMP2_MOUSE (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		306744 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57
+	At
		812701 SNP33_ARATH (29-258): 3.85e-56: 183: 23.04		VA722_ARATH (8-79): 4.28e-31: 110: 31.94
+	At
		1351793 SNP33_ARATH (29-258): 3.85e-56: 183: 23.04		VA721_ARATH (8-79): 2.15e-30: 108: 31.94
+	Hs
		117935 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00
+	Hs
		118036 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		117995 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		118017 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		118071 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Rn
		250769 SNP23_RAT (43-258): 1.08e-55: 179: 20.83		VAMP3_RAT (3-80): 1.57e-24: 90.4: 96.15
+	Hs
		117941 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57
+	Hs
		66336 A8K287_HUMAN (41-258): 1.14e-58: 187: 20.18		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57
+	Rn
		250770 SNP23_RAT (43-258): 1.08e-55: 179: 20.83		VAMP2_RAT (8-84): 1.68e-22: 85.8: 87.01
+	Rn
		250775 SNP23_RAT (43-258): 1.08e-55: 179: 20.83		VAMP8_RAT (6-78): 2.53e-22: 84.6: 35.62