HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: JADE2 (Q9NQC1)
E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15)
Gene: JADE2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	23281010
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 790
+	Hs
		998435 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		JADE1_HUMAN (4-790): 0: 680: 47.56
+	Hs
		998619 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		JADE3_HUMAN (4-780): 0: 597: 40.68
+	Hs
		1161968 H31T_HUMAN (1-136): 1.34e-61: 187: 100.00		JADE3_HUMAN (4-780): 0: 597: 40.68
+	Hs
		342152 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		BRD1_HUMAN (7-790): 0: 585: 21.42
+	Hs
		342201 H31T_HUMAN (1-136): 1.34e-61: 187: 100.00		BRD1_HUMAN (7-790): 0: 585: 21.42
+	Hs
		1162078 H31T_HUMAN (1-136): 1.34e-61: 187: 100.00		BRPF3_HUMAN (2-788): 0: 561: 19.93
+	Hs
		936644 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		BRPF1_HUMAN (7-750): 0: 553: 20.05
+	Hs
		320320 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		PHF14_HUMAN (99-742): 8.02e-116: 375: 19.12
+	Hs
		320324 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		PHF14_HUMAN (99-742): 8.02e-116: 375: 19.12
+	Hs
		998802 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		KDM4C_HUMAN (9-434): 4.61e-89: 305: 20.27
+	Hs
		936539 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		AF17_HUMAN (195-446): 5.85e-63: 231: 29.37
+	Hs
		161446 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		KMT2D_HUMAN (248-605): 6.52e-61: 226: 14.72
+	Hs
		322652 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		KDM4B_HUMAN (70-412): 2.95e-57: 214: 21.11
+	Hs
		322654 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		KDM4B_HUMAN (70-412): 2.95e-57: 214: 21.11
+	Hs
		273420 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		KDM4A_HUMAN (209-412): 2.09e-52: 199: 28.77
+	Hs
		273432 H31T_HUMAN (1-136): 1.34e-61: 187: 100.00		KDM4A_HUMAN (209-412): 2.09e-52: 199: 28.77
+	Hs
		273422 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		KDM4A_HUMAN (209-412): 2.09e-52: 199: 28.77
+	Hs
		998565 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		KMT2C_HUMAN (270-373): 2.13e-09: 63.5: 25.00
+	Mm
		107469 H33_MOUSE (1-136): 1.86e-61: 186: 93.38		F8WI37_MOUSE (270-373): 7.45e-10: 65.1: 25.00
+	Hs
		1161950 H31T_HUMAN (1-136): 1.34e-61: 187: 100.00		KMT2C_HUMAN (270-373): 2.13e-09: 63.5: 25.00