HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33194618
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 964 Hs			1 165
+	Hs
		323175 TRI37_HUMAN (1-964): 0: 1226: 100.00		PPIB_HUMAN (2-165): 9.5e-88: 257: 63.64
+	Hs
		623258 RO52_HUMAN (1-459): 1.53e-75: 257: 15.61		PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00
+	Hs
		623104 RO52_HUMAN (1-459): 1.53e-75: 257: 15.61		PPIB_HUMAN (2-165): 9.5e-88: 257: 63.64
+	Hs
		571945 TRI27_HUMAN (1-458): 3.63e-69: 241: 14.78		PPID_HUMAN (2-165): 3.39e-88: 263: 59.30
+	Hs
		95720 TRI27_HUMAN (1-458): 3.63e-69: 241: 14.78		E5KN55_HUMAN (2-165): 3.39e-88: 263: 59.30
+	Hs
		719447 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		PPIF_HUMAN (3-164): 6.29e-92: 267: 76.54
+	Hs
		986514 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00
+	Hs
		1064882 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		PPID_HUMAN (2-165): 3.39e-88: 263: 59.30
+	Hs
		1256097 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		PPIE_HUMAN (2-163): 2.09e-88: 262: 67.28
+	Hs
		656164 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		PPIB_HUMAN (2-165): 9.5e-88: 257: 63.64
+	Hs
		216263 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		PPIH_HUMAN (2-164): 1.39e-84: 247: 53.85
+	Hs
		890518 TRI67_HUMAN (10-367): 1e-58: 218: 16.27		RBP2_HUMAN (3-164): 1.88e-73: 240: 66.67