Interactor 1: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain)
Gene: PSMA5

Interactor 2: PSB10 (P40306)
Proteasome subunit beta type-10 (EC 3.4.25.1) (Low molecular mass protein 10) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1) (Proteasome MECl-1) (Proteasome subunit beta-2i)
Gene: PSMB10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pr_beta_C~Proteasome, Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005839 - proteasome core complex
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 241
Hs

1 273
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Sp
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Sc
+ Hs
+ Dm
+ Dm
+ Af
+ Ph

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Last updated: 15 Jul 2024