HitPredict

Interactor 1: AP2A2 (O94973)
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene: AP2A2

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	23383273, 37776851
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008289 - lipid binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 939 Hs			1 806
+	Hs
		344659 AP2A1_HUMAN (1-939): 0: 832: 78.47		TERA_HUMAN (1-806): 0: 774: 100.00
+	Hs
		225790 AP1G1_HUMAN (1-811): 0: 616: 25.12		TERA_HUMAN (1-806): 0: 774: 100.00
+	Hs
		934427 AP2B1_HUMAN (36-933): 0: 607: 16.62		TERA_HUMAN (1-806): 0: 774: 100.00
+	Hs
		934528 AP1B1_HUMAN (36-934): 0: 606: 17.35		TERA_HUMAN (1-806): 0: 774: 100.00
+	Hs
		158799 AP3D1_HUMAN (11-478): 3.34e-33: 140: 23.51		TERA_HUMAN (1-806): 0: 774: 100.00
+	Sc
		680133 AP3D_YEAST (51-603): 3.01e-19: 95.5: 21.21		CDC48_YEAST (2-806): 0: 740: 67.75
+	Hs
		231721 Q86V28_HUMAN (202-681): 5.63e-37: 150: 27.73		PEX1_HUMAN (9-806): 1.71e-128: 416: 23.77