Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: M4K2 (Q12851)
Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)
Gene: MAP4K2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 32640226, 35027733
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~Pkinase_C, Pkinase~UBA
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0006468 - protein phosphorylation
GO:0106310 - protein serine kinase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1130
Hs

1 820
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+ Dm
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+ Rn
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024