Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2
Interactor 2: 2A5G (Q13362)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-gamma) (PP2A B subunit isoform PR61-gamma) (PP2A B subunit isoform R5-gamma) (Renal carcinoma antigen NY-REN-29)
Gene: PPP2R5C
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 0.60 | 0.660 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23178491, 15380617 |
| Identification Methods | biochemical, two hybrid, pull down, affinity chromatography technology, enzymatic study, tandem affinity purification, anti tag coimmunoprecipitation, protein kinase assay |
| Interaction Type | association, direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005794 - Golgi apparatus GO:0006977 - DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0042771 - intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
