HitPredict

Interactor 1: SODC (P00441)
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1)
Gene: SOD1

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29128334
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043085 - positive regulation of catalytic activity GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 154 Hs			1 246
+	Hs
		336452 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		336461 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Mm
		437607 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02
+	Mm
		437623 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433B_MOUSE (1-246): 5.56e-141: 396: 98.78
+	Hs
		336370 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Mm
		437608 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433T_MOUSE (3-244): 9.37e-127: 360: 81.82
+	Hs
		336448 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Mm
		437605 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433G_MOUSE (3-246): 1.91e-109: 317: 75.40
+	Mm
		437609 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433F_MOUSE (4-244): 8.67e-108: 312: 75.51