HitPredict

Interactor 1: FMNL1 (O95466)
Formin-like protein 1 (CLL-associated antigen KW-13) (Leukocyte formin)
Gene: FMNL1

Interactor 2: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1100 Hs			1 227
+	Hs
		337575 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOB_HUMAN (5-185): 8.64e-92: 269: 45.86
+	Hs
		978231 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RHOB_HUMAN (5-185): 8.64e-92: 269: 45.86
+	Hs
		337573 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOA_HUMAN (9-193): 3.39e-84: 250: 47.03
+	Hs
		337579 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOG_HUMAN (7-193): 2.61e-84: 250: 41.71
+	Hs
		337556 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RAC2_HUMAN (8-195): 7.72e-79: 236: 40.43
+	Hs
		337577 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RAC1_HUMAN (8-194): 9.85e-79: 236: 42.25
+	Hs
		962396 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RHOA_HUMAN (9-193): 3.39e-84: 250: 47.03
+	Hs
		337574 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RB11A_HUMAN (3-224): 1.68e-76: 231: 21.08
+	Hs
		466419 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RHOC_HUMAN (9-193): 5.48e-82: 244: 48.11
+	Hs
		988622 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RAC1_HUMAN (8-194): 9.85e-79: 236: 42.25
+	Hs
		126419 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOD_HUMAN (9-191): 9.06e-55: 176: 43.48
+	Hs
		337615 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOF_HUMAN (9-191): 9.2e-51: 165: 43.01
+	Hs
		126749 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RHOD_HUMAN (9-191): 9.06e-55: 176: 43.48
+	Dm
		828034 FRL_DROME (19-1088): 0: 650: 36.85		RAC1_DROME (8-195): 2.64e-79: 237: 40.43
+	Hs
		988862 FHOD1_HUMAN (185-1099): 1.5e-138: 449: 16.22		RAC1_HUMAN (8-194): 9.85e-79: 236: 42.25
+	Hs
		962240 FMNL3_HUMAN (1-506): 6.39e-130: 423: 60.90		RHOA_HUMAN (9-193): 3.39e-84: 250: 47.03
+	Hs
		581155 FMNL3_HUMAN (1-506): 6.39e-130: 423: 60.90		RAC2_HUMAN (8-195): 7.72e-79: 236: 40.43
+	Hs
		466284 INF2_HUMAN (181-1063): 2.55e-120: 402: 20.27		RHOC_HUMAN (9-193): 5.48e-82: 244: 48.11
+	Hs
		581080 INF2_HUMAN (181-1063): 2.55e-120: 402: 20.27		RAC2_HUMAN (8-195): 7.72e-79: 236: 40.43
+	Hs
		126623 INF2_HUMAN (181-1063): 2.55e-120: 402: 20.27		RHOD_HUMAN (9-191): 9.06e-55: 176: 43.48