HitPredict

Interactor 1: FMNL1 (O95466)
Formin-like protein 1 (CLL-associated antigen KW-13) (Leukocyte formin)
Gene: FMNL1

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 10958683, 31871319
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005938 - cell cortex
GO:0008360 - regulation of cell shape
GO:0016020 - membrane
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1100
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1 192
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Service provided by Combinatics, Japan

Last updated: 11Aug2025