Interactor 1: THRB (P00734)
Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]
Gene: F2

Interactor 2: CBPB2 (Q96IY4)
Carboxypeptidase B2 (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Plasma carboxypeptidase B) (pCPB) (Thrombin-activable fibrinolysis inhibitor) (TAFI)
Gene: CPB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 8663147
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_M14~Trypsin, Propep_M14~Trypsin
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
GO:0007596 - blood coagulation
GO:0042730 - fibrinolysis
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 622
Hs

1 423
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024