Interactor 1: C1R (P00736)
Complement C1r subcomponent (EC 3.4.21.41) (Complement component 1 subcomponent r) [Cleaved into: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain]
Gene: C1R
Interactor 2: C1RL (Q9NZP8)
Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (C1r-like serine protease analog protein) (CLSPa)
Gene: C1RL
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.65 | 1.00 | 0.811 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | CUB~CUB, CUB~FXa_inhibition, FXa_inhibition~Trypsin, CUB~Sushi, Sushi~Trypsin, Trypsin~Trypsin |
Common GO terms | GO:0004252 - serine-type endopeptidase activity GO:0005615 - extracellular space GO:0006958 - complement activation, classical pathway GO:0031638 - zymogen activation GO:0045087 - innate immune response and 2 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024