Interactor 1: CYTC (P01034)
Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin)
Gene: CST3
Interactor 2: LGMN (Q99538)
Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (AEP) (Protease, cysteine 1)
Gene: LGMN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.73 | 1.00 | 0.855 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 25630877 |
| Identification Methods | affinity chromatography technology, thermal shift binding, molecular sieving, protease assay, enzymatic study, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, protein cleavage, enzymatic reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cystatin~Peptidase_C13 |
| Common GO terms | GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0070062 - extracellular exosome |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
