HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.655

Property	Details
Experiments	16055710, 16236267, 17709345
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001221 - transcription coregulator binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 158
+	Hs
		345372 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		547776 ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		930155 CREM_HUMAN (2-188): 4.21e-26: 109: 18.85		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		566745 JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		401812 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		579189 ATF3_HUMAN (131-215): 4.23e-25: 102: 43.53		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00