HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: TRIB1 (Q96RU8)
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)
Gene: TRIB1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.618

Property	Details
Experiments	25609649, 35140242
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032496 - response to lipopolysaccharide GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 372
+	Hs
		610737 CR3L3_HUMAN (5-323): 1.7e-46: 166: 15.46		KAPCB_HUMAN (81-371): 1.77e-130: 379: 20.66
+	Hs
		547787 ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57		KPCE_HUMAN (11-371): 2.39e-128: 387: 17.32
+	Hs
		548261 FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		579370 ATF6A_HUMAN (4-318): 1.09e-31: 128: 14.03		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		548326 FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		402572 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		KS6B2_HUMAN (50-371): 1.22e-125: 371: 20.29
+	Hs
		862631 FOSB_HUMAN (2-380): 1.59e-25: 107: 34.24		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		566786 JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		401319 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		KPSH1_HUMAN (34-341): 7.34e-109: 327: 23.84
+	Hs
		345487 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		548254 FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		579357 ATF6A_HUMAN (4-318): 1.09e-31: 128: 14.03		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		548318 FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		862625 FOSB_HUMAN (2-380): 1.59e-25: 107: 34.24		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		566775 JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		402242 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31