Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC
Interactor 2: CDK4 (P11802)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.82 | 0.60 | 0.702 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28205554, 35013218, 22094256, 21988832 |
| Identification Methods | fluorescent resonance energy transfer, affinity chromatography technology, enzymatic study, two hybrid, two hybrid array, protein kinase assay |
| Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 5 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
