HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: YBOX3 (P16989)
Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB)
Gene: YBX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010468 - regulation of gene expression
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 372
+	Hs
		347120 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LN28B_HUMAN (63-314): 9.71e-58: 190: 22.39
+	Hs
		346476 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89
+	Mm
		348415 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		YBOX1_MOUSE (58-372): 1.42e-51: 176: 45.89
+	Hs
		378991 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00
+	Hs
		379529 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		LN28B_HUMAN (63-314): 9.71e-58: 190: 22.39
+	Hs
		379259 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89
+	Dm
		1278937 MYC_DROME (210-454): 3.25e-30: 126: 26.74		Q95RE4_DROME (79-229): 1.33e-33: 129: 53.64