HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: LIMS1 (P48059)
LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48)
Gene: LIMS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	21150319
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0005737 - cytoplasm GO:0010628 - positive regulation of gene expression
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 325
+	Hs
		347985 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PDLI7_HUMAN (191-324): 1.12e-35: 135: 29.85
+	Hs
		150500 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ABLM1_HUMAN (3-146): 5.18e-26: 110: 22.92
+	Hs
		346762 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FHL2_HUMAN (217-325): 3.32e-13: 70.4: 27.03
+	Hs
		379395 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FHL2_HUMAN (217-325): 3.32e-13: 70.4: 27.03
+	Hs
		1016076 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		ABLM2_HUMAN (2-171): 1.4e-30: 123: 24.18
+	Hs
		150561 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		ABLM1_HUMAN (3-146): 5.18e-26: 110: 22.92
+	Hs
		607818 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		FHL2_HUMAN (217-325): 3.32e-13: 70.4: 27.03
+	Hs
		1016061 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		FHL2_HUMAN (217-325): 3.32e-13: 70.4: 27.03
+	Hs
		1016059 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		FHL3_HUMAN (217-325): 9.05e-13: 69.2: 23.42
+	Hs
		1050646 USF2_HUMAN (180-454): 1.78e-35: 136: 15.99		FHL2_HUMAN (217-325): 3.32e-13: 70.4: 27.03
+	Hs
		252923 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		FHL2_HUMAN (217-325): 3.32e-13: 70.4: 27.03