HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: SYMC (P56192)
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)
Gene: MARS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	29467282, 36424410, 17314511, 17353931
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 900
+	Hs
		379175 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SYMC_HUMAN (1-900): 0: 915: 100.00
+	Hs
		345978 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SYVC_HUMAN (404-899): 4.62e-95: 327: 12.54
+	Hs
		346143 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SYIC_HUMAN (226-458): 4.87e-42: 168: 11.81