HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30415952, 35013218, 36424410
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 342
+	Hs
		346901 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		346628 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		302234 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SC31A_HUMAN (23-342): 1.55e-55: 197: 17.56
+	Hs
		347980 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38
+	Hs
		347550 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (249-341): 1.44e-21: 97.2: 15.05
+	Hs
		347728 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61
+	Hs
		302236 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SC31A_HUMAN (23-342): 1.55e-55: 197: 17.56
+	Hs
		607823 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		607812 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		379701 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		1218698 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Dm
		1249261 MYC_DROME (210-454): 3.25e-30: 126: 26.74		Q8SYL1_DROME (125-326): 1.89e-20: 93.7: 20.18
+	Mm
		659344 MAX_MOUSE (354-454): 3.52e-25: 102: 32.67		WDR5_MOUSE (208-342): 8.98e-29: 115: 11.85
+	Hs
		1218714 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61