HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: RNF12 (Q9NVW2)
E3 ubiquitin-protein ligase RLIM (EC 2.3.2.27) (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (RING finger protein 12) (RING-type E3 ubiquitin transferase RLIM) (Renal carcinoma antigen NY-REN-43)
Gene: RLIM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29137325
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 624
+	Hs
		282453 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RNF8_HUMAN (330-614): 2.23e-34: 138: 11.15
+	Hs
		348345 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RN115_HUMAN (423-621): 3.75e-33: 131: 20.90
+	Hs
		347227 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GOLI_HUMAN (522-617): 2.5e-31: 128: 33.01
+	Hs
		207532 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RNF13_HUMAN (550-618): 7.56e-30: 123: 42.86
+	Hs
		207533 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RNF13_HUMAN (550-618): 7.56e-30: 123: 42.86
+	Mm
		291319 MYCB_MOUSE (16-189): 8.18e-37: 134: 58.05		TTC3_MOUSE (172-619): 2.92e-45: 175: 13.38
+	Hs
		1016088 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		ZNRF4_HUMAN (558-617): 1.08e-10: 66.2: 43.55