HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 270
+	Hs
		589152 MINK1_HUMAN (1-1239): 0: 1130: 59.29		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		589997 TNIK_HUMAN (1-1239): 0: 1115: 60.45		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		587969 MARK3_HUMAN (16-680): 1.75e-129: 417: 15.10		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		588587 AAPK1_HUMAN (8-555): 2.04e-123: 394: 16.85		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		588009 AKT2_HUMAN (2-354): 3.96e-124: 393: 21.98		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		588008 AKT1_HUMAN (2-354): 1.3e-122: 389: 20.82		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		588997 MARK2_HUMAN (19-772): 2.97e-118: 388: 16.14		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		270768 ROCK2_HUMAN (15-536): 6.69e-107: 370: 22.02		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		590124 M4K5_HUMAN (4-375): 4.26e-107: 359: 39.52		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		589913 STK26_HUMAN (16-414): 4.37e-111: 356: 34.05		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00
+	Hs
		590163 STK24_HUMAN (20-398): 1.11e-110: 356: 36.65		RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00