HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: UACA (Q9BZF9)
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene: UACA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1416
+	Hs
		350518 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		UACA_HUMAN (3-1323): 6.02e-45: 180: 14.97
+	Hs
		1070380 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		UACA_HUMAN (3-1323): 6.02e-45: 180: 14.97
+	Hs
		350674 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		1070450 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		350123 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		1021405 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		349000 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		349621 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		UACA_HUMAN (3-1323): 6.02e-45: 180: 14.97
+	Hs
		914450 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		895318 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Dm
		1248518 Q962I2_DROME (4-170): 1.83e-59: 186: 51.79		Q8SWY2_DROME (43-399): 1.27e-52: 203: 14.01
+	Hs
		350626 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		1070426 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		914416 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		350675 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ANR50_HUMAN (180-367): 2.17e-10: 67.9: 15.07
+	Hs
		349001 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		ANR50_HUMAN (180-367): 2.17e-10: 67.9: 15.07
+	Hs
		349212 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DAPK1_HUMAN (160-397): 1.88e-10: 67.9: 11.67
+	Hs
		862018 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		DAPK1_HUMAN (160-397): 1.88e-10: 67.9: 11.67
+	Hs
		914199 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		HACE1_HUMAN (102-374): 1.34e-09: 65.1: 25.52