HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: SPY4 (Q9C004)
Protein sprouty homolog 4 (Spry-4)
Gene: SPRY4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30442766, 30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 299
+	Hs
		350521 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		1070382 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		349623 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		914338 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		895255 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		208084 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SPY2_HUMAN (27-291): 9.66e-99: 294: 39.86
+	Hs
		208083 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		SPY2_HUMAN (27-291): 9.66e-99: 294: 39.86
+	Hs
		350297 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SPRE2_HUMAN (115-264): 1.21e-47: 166: 19.36
+	Hs
		914173 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		SPRE1_HUMAN (97-259): 6.2e-51: 175: 21.30
+	Hs
		1079931 RB11B_HUMAN (4-184): 2.97e-73: 221: 32.79		SPRE1_HUMAN (97-259): 6.2e-51: 175: 21.30