HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: AP3M2 (P53677)
AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B)
Gene: AP3M2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0006897 - endocytosis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 418
+	Hs
		350710 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		AP3M1_HUMAN (1-418): 8.75e-165: 471: 84.21
+	Hs
		350440 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		AP2M1_HUMAN (1-417): 6.29e-151: 436: 24.89
+	Hs
		897974 RAP1B_HUMAN (1-165): 2.18e-63: 195: 57.49		AP3M1_HUMAN (1-418): 8.75e-165: 471: 84.21
+	Hs
		349558 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		AP2M1_HUMAN (1-417): 6.29e-151: 436: 24.89
+	Hs
		119701 RALA_HUMAN (4-168): 3.3e-59: 185: 54.22		AP4M1_HUMAN (1-417): 8.92e-117: 350: 20.52
+	Hs
		350403 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		STON2_HUMAN (29-416): 1.32e-60: 212: 12.90
+	Hs
		350747 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		STON1_HUMAN (160-406): 7.18e-57: 201: 11.61