Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS
Interactor 2: RIN1 (Q13671)
Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1)
Gene: RIN1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.982 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 33961781, 15886098, 15031288, 7862125, 34591612, 9144171, 24441586, 10545207, 11784866, 34591642 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, biochemical, coimmunoprecipitation, genetic interference, nuclear magnetic resonance, surface plasmon resonance, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RA~Ras, Ras~VPS9 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0007165 - signal transduction |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
