HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: CD276 (Q5ZPR3)
CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276)
Gene: CD276

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0032729 - positive regulation of type II interferon production GO:0050852 - T cell receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 534
+	Hs
		348723 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CD276_HUMAN (1-534): 8.41e-136: 405: 100.00
+	Hs
		350246 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CD276_HUMAN (1-534): 8.41e-136: 405: 100.00
+	Hs
		350065 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		BT3A2_HUMAN (230-532): 1.27e-77: 249: 24.68
+	Hs
		348867 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		KIRR1_HUMAN (10-529): 1.49e-67: 233: 13.88
+	Hs
		350455 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		KIRR1_HUMAN (10-529): 1.49e-67: 233: 13.88
+	Hs
		130189 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		BT3A3_HUMAN (230-532): 1.42e-78: 259: 25.32
+	Hs
		349043 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ROBO1_HUMAN (139-533): 1.17e-55: 204: 14.21
+	Hs
		914281 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		KIRR1_HUMAN (10-529): 1.49e-67: 233: 13.88
+	Hs
		349572 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		KIRR1_HUMAN (10-529): 1.49e-67: 233: 13.88
+	Hs
		350746 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO1_HUMAN (139-533): 1.17e-55: 204: 14.21
+	Hs
		348489 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NCAM1_HUMAN (149-533): 2.2e-48: 181: 14.50
+	Hs
		349841 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NCAM1_HUMAN (149-533): 2.2e-48: 181: 14.50
+	Hs
		914506 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		ROBO1_HUMAN (139-533): 1.17e-55: 204: 14.21
+	Hs
		349096 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		NCAM1_HUMAN (149-533): 2.2e-48: 181: 14.50
+	Hs
		350572 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO2_HUMAN (1-376): 1.08e-34: 141: 14.99
+	Hs
		914415 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		PD1L1_HUMAN (15-268): 5.59e-44: 159: 27.73
+	Mm
		919005 RAB1A_MOUSE (4-186): 2.67e-75: 226: 31.28		PD1L1_MOUSE (17-271): 2.06e-42: 155: 24.90
+	Mm
		804674 RB11B_MOUSE (4-171): 1.14e-72: 220: 34.12		PD1L1_MOUSE (17-271): 2.06e-42: 155: 24.90
+	Hs
		350405 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		TITIN_HUMAN (57-462): 8.86e-10: 63.9: 10.02
+	Hs
		914253 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		TITIN_HUMAN (57-462): 8.86e-10: 63.9: 10.02