Protein: UBF1
Nucleolar transcription factor 1 (Autoantigen NOR-90) (Upstream-binding factor 1) (UBF-1)

Gene: UBF1, UBTF
Organism: Homo sapiens
Interactions: 208
UniProt ID: P17480

Gene Ontology (top 5):
GO:0001164 - RNA polymerase I core promoter sequence-specific DNA binding
GO:0001165 - RNA polymerase I cis-regulatory region sequence-specific DNA binding
GO:0001181 - RNA polymerase I general transcription initiation factor activity
GO:0001650 - fibrillar center
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

567662

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

2

0

High-throughput

0.770

High

345860

MYC
Myc proto-oncogene protein

5

19

High-throughput

0.699

High

567772

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.691

High

567774

SIR7
NAD-dependent protein deacetylase sirtuin-7

4

5

Small-scale

0.680

High

149966

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

3

3

High-throughput

0.667

High

414157

RB
Retinoblastoma-associated protein

2

3

Small-scale

0.653

High

567692

RUNX2
Runt-related transcription factor 2

3

8

Small-scale

0.646

High

243890

BRD4
Bromodomain-containing protein 4

3

18

High-throughput

0.640

High

317068

RPA1
DNA-directed RNA polymerase I subunit RPA1

3

4

Small-scale

0.640

High

567697

CHD4
Chromodomain-helicase-DNA-binding protein 4

3

20

Small-scale

0.640

High

132090

PESC
Pescadillo homolog

2

1

High-throughput

0.628

High

488894

H14
Histone H1.4

2

7

High-throughput

0.628

High

567657

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

2

High-throughput

0.628

High

567739

KAT5
Histone acetyltransferase KAT5

2

1

Small-scale

0.624

High

567658

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.618

High

567787

LEF1
Lymphoid enhancer-binding factor 1

1

20

Small-scale

0.618

High

133307

NOP56
Nucleolar protein 56

2

4

High-throughput

0.611

High

567738

EDA
Ectodysplasin-A

3

3

High-throughput

0.609

High

567714

RSBN1
Lysine-specific demethylase 9

2

0

High-throughput

0.602

High

567782

CPNE7
Copine-7

2

0

High-throughput

0.602

High

179535

RPA34
DNA-directed RNA polymerase I subunit RPA34

2

8

Small-scale

0.595

High

567765

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

1

Small-scale

0.595

High

567651

IRS1
Insulin receptor substrate 1

2

9

Small-scale

0.584

High

567668

H2B1C
Histone H2B type 1-C/E/F/G/I

2

17

High-throughput

0.584

High

567673

H31
Histone H3.1

2

20

High-throughput

0.584

High

567754

MBB1A
Myb-binding protein 1A

2

1

Small-scale

0.584

High

567678

SET
Protein SET

1

9

Small-scale

0.578

High

567704

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

2

0

Small-scale

0.577

High

567731

CAMKV
CaM kinase-like vesicle-associated protein

2

1

High-throughput

0.574

High

567677

MDM2
E3 ubiquitin-protein ligase Mdm2

2

1

Small-scale

0.571

High

567660

CEBPA
CCAAT/enhancer-binding protein alpha

2

20

Small-scale

0.563

High

567634

TAF1
Transcription initiation factor TFIID subunit 1

1

20

Small-scale

0.552

High

567672

CSK21
Casein kinase II subunit alpha

1

7

Small-scale

0.536

High

61302

CNOT1
CCR4-NOT transcription complex subunit 1

1

1

High-throughput

0.536

High

368940

ESR1
Estrogen receptor

1

20

High-throughput

0.536

High

443313

VIME
Vimentin

1

8

High-throughput

0.536

High

528493

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

567644

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

567654

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

2

High-throughput

0.536

High

567671

SUMO1
Small ubiquitin-related modifier 1

1

8

High-throughput

0.536

High

567674

SRPK2
SRSF protein kinase 2

1

12

High-throughput

0.536

High

567676

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

15

High-throughput

0.536

High

567682

TLE1
Transducin-like enhancer protein 1

1

20

Small-scale

0.536

High

567684

ZN543
Zinc finger protein 543

1

2

High-throughput

0.536

High

567696

ZN460
Zinc finger protein 460

1

3

High-throughput

0.536

High

567709

RN151
RING finger protein 151

1

12

High-throughput

0.536

High

567727

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

3

High-throughput

0.536

High

567734

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

2

High-throughput

0.536

High

567753

MPP8
M-phase phosphoprotein 8

1

13

High-throughput

0.536

High

567776

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.536

High

567793

MB212
Protein mab-21-like 2

1

5

High-throughput

0.536

High

567755

SLF1
SMC5-SMC6 complex localization factor protein 1

1

13

High-throughput

0.515

High

567783

ZMYM2
Zinc finger MYM-type protein 2

1

3

Small-scale

0.515

High

567769

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

Small-scale

0.513

High

567708

KNOP1
Lysine-rich nucleolar protein 1

1

0

High-throughput

0.513

High

567756

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.513

High

567781

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

567784

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

567661

GSK3A
Glycogen synthase kinase-3 alpha

1

4

High-throughput

0.508

High

160366

AURKA
Aurora kinase A

1

4

Small-scale

0.501

High

515326

CDK4
Cyclin-dependent kinase 4

1

11

Small-scale

0.501

High

567639

CCND1
G1/S-specific cyclin-D1

1

3

Small-scale

0.501

High

567640

CCNE1
G1/S-specific cyclin-E1

1

2

Small-scale

0.501

High

567641

CDK2
Cyclin-dependent kinase 2

1

8

Small-scale

0.501

High

567643

MK03
Mitogen-activated protein kinase 3

1

6

Small-scale

0.501

High

567647

MK01
Mitogen-activated protein kinase 1

1

6

Small-scale

0.501

High

567681

CENPC
Centromere protein C

1

4

Small-scale

0.501

High

567685

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.501

High

567705

TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A

1

1

Small-scale

0.501

High

567740

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

8

High-throughput

0.501

High

567665

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.489

High

567722

PNM8A
Paraneoplastic antigen-like protein 8A

1

2

High-throughput

0.489

High

567736

JPH3
Junctophilin-3

1

4

High-throughput

0.489

High

567766

TOLIP
Toll-interacting protein

1

1

High-throughput

0.489

High

567794

WIF1
Wnt inhibitory factor 1

1

3

High-throughput

0.489

High

567712

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

1

0

Small-scale

0.480

High

122481

MEN1
Menin

1

2

High-throughput

0.479

High

125141

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

11

High-throughput

0.479

High

148370

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.479

High

180208

MAGB2
Melanoma-associated antigen B2

1

5

Small-scale

0.479

High

211490

ACTN4
Alpha-actinin-4

1

7

Small-scale

0.479

High

229300

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

Small-scale

0.479

High

233200

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

239299

CC14B
Dual specificity protein phosphatase CDC14B

1

6

High-throughput

0.479

High

257908

DNJB6
DnaJ homolog subfamily B member 6

1

9

High-throughput

0.479

High

278728

DNJC8
DnaJ homolog subfamily C member 8

1

7

High-throughput

0.479

High

298129

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

316785

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

567759

KLF16
Krueppel-like factor 16

1

16

High-throughput

0.479

High

322153

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.479

High

359638

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

17

Small-scale

0.479

High

378995

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

397763

ISG15
Ubiquitin-like protein ISG15

1

4

High-throughput

0.479

High

455065

PARP1
Poly [ADP-ribose] polymerase 1

1

16

High-throughput

0.479

High

487108

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

551895

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

567631

CEBPB
CCAAT/enhancer-binding protein beta

1

20

High-throughput

0.479

High

567632

TBP
TATA-box-binding protein

1

1

Small-scale

0.479

High

567633

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

567638

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

High-throughput

0.479

High

567642

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

567645

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

567646

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

567649

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

567650

RL22
Large ribosomal subunit protein eL22

1

4

High-throughput

0.479

High

567652

BRCA1
Breast cancer type 1 susceptibility protein

1

6

Small-scale

0.479

High

567653

COIL
Coilin

1

2

High-throughput

0.479

High

567659

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

567663

FOXA1
Hepatocyte nuclear factor 3-alpha

1

20

High-throughput

0.479

High

567666

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.479

High

567667

H4
Histone H4

1

11

High-throughput

0.479

High

567669

RS24
Small ribosomal subunit protein eS24

1

2

High-throughput

0.479

High

567670

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.479

High

567675

H33
Histone H3.3

1

20

High-throughput

0.479

High

567679

EWS
RNA-binding protein EWS

1

12

High-throughput

0.479

High

567680

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

567683

UBE3A
Ubiquitin-protein ligase E3A

1

11

High-throughput

0.479

High

567686

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

567687

NFX1
Transcriptional repressor NF-X1

1

3

High-throughput

0.479

High

567688

CBX3
Chromobox protein homolog 3

1

15

High-throughput

0.479

High

567690

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

567691

HDAC1
Histone deacetylase 1

1

15

Small-scale

0.479

High

567693

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

16

High-throughput

0.479

High

567694

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.479

High

567699

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

20

Small-scale

0.479

High

567700

SUZ12
Polycomb protein SUZ12

1

3

High-throughput

0.479

High

567701

TNIP1
TNFAIP3-interacting protein 1

1

10

High-throughput

0.479

High

567702

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

567703

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

567706

EZH2
Histone-lysine N-methyltransferase EZH2

1

14

High-throughput

0.479

High

567707

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

567710

LARP7
La-related protein 7

1

17

High-throughput

0.479

High

567713

MYSM1
Deubiquitinase MYSM1

1

20

Small-scale

0.479

High

567716

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

567719

H32
Histone H3.2

1

20

Small-scale

0.479

High

567721

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

567724

DHX40
Probable ATP-dependent RNA helicase DHX40

1

4

High-throughput

0.479

High

567725

SMC5
Structural maintenance of chromosomes protein 5

1

12

High-throughput

0.479

High

567726

SLX4
Structure-specific endonuclease subunit SLX4

1

9

High-throughput

0.479

High

567728

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

9

High-throughput

0.479

High

567729

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.479

High

567730

CGAS
Cyclic GMP-AMP synthase

1

5

High-throughput

0.479

High

567733

NUP43
Nucleoporin Nup43

1

19

High-throughput

0.479

High

567735

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

567737

DNJC9
DnaJ homolog subfamily C member 9

1

9

High-throughput

0.479

High

567741

FBXW7
F-box/WD repeat-containing protein 7

1

10

High-throughput

0.479

High

567742

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

13

High-throughput

0.479

High

567746

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

15

High-throughput

0.479

High

567748

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

567750

PSB7
Proteasome subunit beta type-7

1

1

High-throughput

0.479

High

567751

CDC5L
Cell division cycle 5-like protein

1

5

High-throughput

0.479

High

567752

RING2
E3 ubiquitin-protein ligase RING2

1

19

High-throughput

0.479

High

567757

DDX23
Probable ATP-dependent RNA helicase DDX23

1

9

High-throughput

0.479

High

567758

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

567762

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

8

High-throughput

0.479

High

567764

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

567767

CHM4B
Charged multivesicular body protein 4b

1

6

High-throughput

0.479

High

567768

SENP3
Sentrin-specific protease 3

1

2

Small-scale

0.479

High

567770

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.479

High

567771

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

567773

ANLN
Anillin

1

4

High-throughput

0.479

High

567775

DJC17
DnaJ homolog subfamily C member 17

1

10

High-throughput

0.479

High

567778

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

4

High-throughput

0.479

High

567780

NOP53
Ribosome biogenesis protein NOP53

1

2

Small-scale

0.479

High

567786

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

567789

FBW1A
F-box/WD repeat-containing protein 1A

1

12

High-throughput

0.479

High

567791

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

182541

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

211740

BUD23
Probable 18S rRNA

1

0

Small-scale

0.458

High

567711

MIDN
Midnolin

1

0

High-throughput

0.458

High

567732

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

567744

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

567747

MCRS1
Microspherule protein 1

1

0

Small-scale

0.458

High

567749

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

567779

RRN3
RNA polymerase I-specific transcription initiation factor RRN3

1

0

Small-scale

0.458

High

567760

HEMGN
Hemogen

1

2

Small-scale

0.445

High

255488

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.437

High

384221

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.437

High

486457

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.437

High

567636

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

7

Small-scale

0.437

High

567648

GRK5
G protein-coupled receptor kinase 5

1

5

High-throughput

0.437

High

567655

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

Small-scale

0.437

High

567698

CUL7
Cullin-7

1

3

High-throughput

0.437

High

567715

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.437

High

567717

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.437

High

567745

CHM4C
Charged multivesicular body protein 4c

1

6

High-throughput

0.437

High

567761

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

567763

TRI31
E3 ubiquitin-protein ligase TRIM31

1

5

High-throughput

0.437

High

567777

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

567788

HECD1
E3 ubiquitin-protein ligase HECTD1

1

13

High-throughput

0.437

High

567792

IRS2
Insulin receptor substrate 2

1

9

Small-scale

0.437

High

48613

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.426

High

393766

SCG1
Secretogranin-1

1

5

High-throughput

0.417

High

239758

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.407

High

567656

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

0

High-throughput

0.347

High

567785

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

0

High-throughput

0.347

High

567635

MK
Midkine

2

0

High-throughput

0.328

High

567718

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

483473

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

567689

NOGG
Noggin

1

0

High-throughput

0.279

Low

567695

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

567720

GOGA7
Golgin subfamily A member 7

1

0

High-throughput

0.279

Low

567723

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

567790

KLH20
Kelch-like protein 20

1

0

High-throughput

0.279

Low

567664

EVC
EvC complex member EVC

1

0

High-throughput

0.269

Low

314221

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.249

Low

567637

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

Small-scale

0.249

Low

567743

CC049
Putative uncharacterized protein C3orf49

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024