HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: CSKI2 (Q8WXE0)
Caskin-2 (CASK-interacting protein 2)
Gene: CASKIN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1202
+	Hs
		350402 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CSKI2_HUMAN (1-1202): 1.75e-114: 387: 100.00
+	Hs
		349000 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		KDIS_HUMAN (1-302): 1.57e-71: 265: 22.91
+	Hs
		350674 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		KDIS_HUMAN (1-302): 1.57e-71: 265: 22.91
+	Mm
		1206680 RAB1B_MOUSE (4-185): 1.54e-74: 224: 30.93		ANS1B_MOUSE (1-610): 6.14e-79: 286: 23.75
+	Hs
		862018 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		DAPK1_HUMAN (6-585): 7.81e-75: 274: 15.56
+	Hs
		349212 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		DAPK1_HUMAN (6-585): 7.81e-75: 274: 15.56
+	Hs
		914450 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		KDIS_HUMAN (1-302): 1.57e-71: 265: 22.91
+	Dm
		1248518 Q962I2_DROME (4-181): 2.02e-61: 191: 50.82		Q8SWY2_DROME (1-662): 9.17e-83: 294: 16.93
+	Hs
		349001 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ANR50_HUMAN (63-902): 1.51e-56: 217: 13.49
+	Hs
		350675 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ANR50_HUMAN (63-902): 1.51e-56: 217: 13.49
+	Hs
		297805 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		K0754_HUMAN (628-980): 4.7e-43: 174: 17.38
+	Hs
		297806 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		K0754_HUMAN (628-980): 4.7e-43: 174: 17.38
+	Hs
		350414 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ANS1A_HUMAN (295-740): 2.77e-14: 80.3: 22.20
+	Hs
		350123 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ANK3_HUMAN (56-264): 1.05e-09: 65.5: 28.23
+	Hs
		350083 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ANK2_HUMAN (315-1185): 2.96e-09: 63.9: 11.00
+	Dm
		65552 RALA_DROME (4-167): 1.35e-61: 191: 55.15		A8JNM5_DROME (142-448): 1.75e-23: 110: 17.86
+	Hs
		349253 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		ANK2_HUMAN (315-1185): 2.96e-09: 63.9: 11.00