HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: CADM1 (Q9BY67)
Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)
Gene: CADM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 442
+	Hs
		350513 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CADM1_HUMAN (1-442): 2.03e-85: 270: 100.00
+	Hs
		348943 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT3_HUMAN (52-439): 4.89e-73: 240: 23.25
+	Hs
		348808 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CADM4_HUMAN (45-442): 2.31e-72: 234: 34.93
+	Hs
		350584 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT3_HUMAN (52-439): 4.89e-73: 240: 23.25
+	Hs
		348671 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT1_HUMAN (28-410): 5.14e-64: 216: 23.42
+	Hs
		350183 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT1_HUMAN (28-410): 5.14e-64: 216: 23.42
+	Hs
		914381 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		NECT3_HUMAN (52-439): 4.89e-73: 240: 23.25
+	Hs
		349043 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		350746 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		349330 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		NECT1_HUMAN (28-410): 5.14e-64: 216: 23.42
+	Hs
		914506 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		348867 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		KIRR1_HUMAN (12-245): 2.39e-18: 89.5: 13.33
+	Hs
		350455 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		KIRR1_HUMAN (12-245): 2.39e-18: 89.5: 13.33
+	Hs
		348836 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT2_HUMAN (109-334): 8.32e-15: 78.2: 27.07
+	Hs
		350572 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO2_HUMAN (6-364): 6.1e-15: 79.5: 12.94
+	Hs
		350416 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT2_HUMAN (109-334): 8.32e-15: 78.2: 27.07
+	Hs
		914281 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		KIRR1_HUMAN (12-245): 2.39e-18: 89.5: 13.33
+	Hs
		350405 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		TITIN_HUMAN (135-439): 9.8e-09: 59.9: 14.38
+	Hs
		914262 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		NECT2_HUMAN (109-334): 8.32e-15: 78.2: 27.07
+	Hs
		914253 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		TITIN_HUMAN (135-439): 9.8e-09: 59.9: 14.38