Protein: ERMP1
Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina)

Gene: ERMP1
Organism: Homo sapiens
Interactions: 181
UniProt ID: Q7Z2K6

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0006508 - proteolysis
GO:0008235 - metalloexopeptidase activity
GO:0016020 - membrane
GO:0030968 - endoplasmic reticulum unfolded protein response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1275427

CLC2D
C-type lectin domain family 2 member D

4

5

High-throughput

0.689

High

1275378

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

3

0

High-throughput

0.638

High

902352

SCNND
Epithelial sodium channel subunit delta

2

2

High-throughput

0.628

High

1005543

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

3

2

High-throughput

0.609

High

1275380

5HT3C
5-hydroxytryptamine receptor 3C

3

3

High-throughput

0.609

High

1275433

GPR52
G-protein coupled receptor 52

3

4

High-throughput

0.609

High

138567

CLD5
Claudin-5

2

2

High-throughput

0.606

High

832634

AQP2
Aquaporin-2

2

2

High-throughput

0.606

High

1275385

HMR1
Major histocompatibility complex class I-related protein 1

2

4

High-throughput

0.606

High

1275387

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.606

High

1275394

TMM80
Transmembrane protein 80

2

1

High-throughput

0.606

High

1032603

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.602

High

800298

INGR2
Interferon gamma receptor 2

2

0

High-throughput

0.580

High

1275375

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.580

High

1275379

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.580

High

1275395

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

1275405

B2L13
Bcl-2-like protein 13

2

0

High-throughput

0.580

High

1275416

TM45A
Transmembrane protein 45A

2

0

High-throughput

0.580

High

1275435

IR3IP
Immediate early response 3-interacting protein 1

2

0

High-throughput

0.580

High

230980

TYOBP
TYRO protein tyrosine kinase-binding protein

2

0

High-throughput

0.576

High

127696

TR10A
Tumor necrosis factor receptor superfamily member 10A

2

1

High-throughput

0.574

High

835308

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

3

High-throughput

0.574

High

855341

5HT3A
5-hydroxytryptamine receptor 3A

2

3

High-throughput

0.574

High

937587

CAD13
Cadherin-13

2

1

High-throughput

0.574

High

1251767

S39A5
Zinc transporter ZIP5

2

2

High-throughput

0.574

High

1275401

GPR21
Probable G-protein coupled receptor 21

2

3

High-throughput

0.574

High

396405

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

1192248

ZACN
Ligand-gated cation channel ZACN

2

4

High-throughput

0.558

High

50110

S22AN
Solute carrier family 22 member 23

2

3

High-throughput

0.553

High

142100

PEX12
Peroxisome assembly protein 12

2

1

High-throughput

0.553

High

337888

CLD7
Claudin-7

2

2

High-throughput

0.553

High

338258

CLD9
Claudin-9

2

2

High-throughput

0.553

High

688582

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

2

5

High-throughput

0.553

High

728873

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

1

High-throughput

0.553

High

870739

CXA8
Gap junction alpha-8 protein

2

3

High-throughput

0.553

High

1108944

AQP6
Aquaporin-6

2

2

High-throughput

0.553

High

1207532

F209A
Protein FAM209A

2

1

High-throughput

0.553

High

1275374

S7A14
Solute carrier family 7 member 14

2

2

High-throughput

0.553

High

1275402

PD1L2
Programmed cell death 1 ligand 2

2

1

High-throughput

0.553

High

1275418

GPC5D
G-protein coupled receptor family C group 5 member D

2

3

High-throughput

0.553

High

1275421

RHCG
Ammonium transporter Rh type C

2

2

High-throughput

0.553

High

1275425

KCNN3
Small conductance calcium-activated potassium channel protein 3

2

1

High-throughput

0.553

High

1275428

S13A4
Solute carrier family 13 member 4

2

1

High-throughput

0.553

High

1275430

HHLA2
HERV-H LTR-associating protein 2

2

1

High-throughput

0.553

High

1275431

AT1B4
Protein ATP1B4

2

1

High-throughput

0.553

High

907026

CCR6
C-C chemokine receptor type 6

2

4

High-throughput

0.549

High

1275419

GPC5B
G-protein coupled receptor family C group 5 member B

2

3

High-throughput

0.549

High

125025

KCNK1
Potassium channel subfamily K member 1

1

1

High-throughput

0.536

High

130145

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.536

High

132617

UPK1A
Uroplakin-1a

1

8

High-throughput

0.536

High

182625

GP182
G-protein coupled receptor 182

1

7

High-throughput

0.536

High

380448

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

3

High-throughput

0.536

High

437713

HEPS
Serine protease hepsin

1

3

High-throughput

0.536

High

669018

FPR2
N-formyl peptide receptor 2

1

7

High-throughput

0.536

High

723237

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

1

High-throughput

0.536

High

851154

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

1

High-throughput

0.536

High

878046

AGRE5
Adhesion G protein-coupled receptor E5

1

2

High-throughput

0.536

High

1238993

NIPA3
Magnesium transporter NIPA3

1

2

High-throughput

0.536

High

1242835

S39A4
Zinc transporter ZIP4

1

2

High-throughput

0.536

High

1275384

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

2

High-throughput

0.536

High

1275386

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

1275391

RN185
E3 ubiquitin-protein ligase RNF185

1

1

High-throughput

0.536

High

1275393

CREL1
Protein disulfide isomerase CRELD1

1

2

High-throughput

0.536

High

1275399

KCNKG
Potassium channel subfamily K member 16

1

1

High-throughput

0.536

High

1275410

RXFP1
Relaxin receptor 1

1

2

High-throughput

0.536

High

117004

J3KQ12
Seipin

1

1

High-throughput

0.515

High

692217

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.513

High

876355

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.513

High

1244874

NCEH1
Neutral cholesterol ester hydrolase 1

1

0

High-throughput

0.513

High

1273238

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

1275392

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.513

High

1275408

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1275434

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

141843

ACKR2
Atypical chemokine receptor 2

1

5

High-throughput

0.489

High

154842

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

1

High-throughput

0.489

High

165974

FFAR1
Free fatty acid receptor 1

1

10

High-throughput

0.489

High

248480

O10H2
Olfactory receptor 10H2

1

2

High-throughput

0.489

High

349461

TSN15
Tetraspanin-15

1

7

High-throughput

0.489

High

351916

S1PR4
Sphingosine 1-phosphate receptor 4

1

5

High-throughput

0.489

High

438894

CD1A
T-cell surface glycoprotein CD1a

1

5

High-throughput

0.489

High

575669

GPIX
Platelet glycoprotein IX

1

3

High-throughput

0.489

High

733010

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

2

High-throughput

0.489

High

771783

SCN4A
Sodium channel protein type 4 subunit alpha

1

1

High-throughput

0.489

High

833833

P2RY2
P2Y purinoceptor 2

1

6

High-throughput

0.489

High

1006019

ASIC1
Acid-sensing ion channel 1

1

2

High-throughput

0.489

High

1049482

1433F
14-3-3 protein eta

1

1

High-throughput

0.489

High

1101553

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

6

High-throughput

0.489

High

1157620

ASIC2
Acid-sensing ion channel 2

1

2

High-throughput

0.489

High

1203700

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.489

High

1216654

OR2G6
Olfactory receptor 2G6

1

1

High-throughput

0.489

High

1254056

LRC55
Leucine-rich repeat-containing protein 55

1

2

High-throughput

0.489

High

1275361

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

8

High-throughput

0.489

High

1275371

OR2M7
Olfactory receptor 2M7

1

1

High-throughput

0.489

High

1275382

LPAR1
Lysophosphatidic acid receptor 1

1

5

High-throughput

0.489

High

1275409

LPAR2
Lysophosphatidic acid receptor 2

1

5

High-throughput

0.489

High

1275414

GP173
Probable G-protein coupled receptor 173

1

2

High-throughput

0.489

High

1275417

SC5A4
Probable glucose sensor protein SLC5A4

1

1

High-throughput

0.489

High

926797

VMAT1
Chromaffin granule amine transporter

1

5

High-throughput

0.481

High

1275390

BSCL2
Seipin

1

1

High-throughput

0.481

High

1275423

S23A2
Solute carrier family 23 member 2

1

1

High-throughput

0.481

High

1136249

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.479

High

1275366

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.479

High

1275367

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.479

High

1275388

PLD4
5'-3' exonuclease PLD4

1

1

High-throughput

0.479

High

193423

GPR42
G-protein coupled receptor 42

1

9

High-throughput

0.470

High

1275429

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.458

High

170840

CLGN
Calmegin

1

2

High-throughput

0.445

High

351230

MOT3
Monocarboxylate transporter 3

1

2

High-throughput

0.445

High

722505

CTR1
High affinity cationic amino acid transporter 1

1

2

High-throughput

0.445

High

727518

SC5A2
Sodium/glucose cotransporter 2

1

1

High-throughput

0.445

High

870253

S6A12
Sodium- and chloride-dependent betaine transporter

1

2

High-throughput

0.445

High

870370

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

2

High-throughput

0.445

High

1007443

S35B1
Solute carrier family 35 member B1

1

2

High-throughput

0.445

High

1131558

MFS10
Major facilitator superfamily domain-containing protein 10

1

4

High-throughput

0.445

High

1139473

S39AE
Metal cation symporter ZIP14

1

2

High-throughput

0.445

High

1242148

NPAL3
NIPA-like protein 3

1

2

High-throughput

0.445

High

1275372

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

4

High-throughput

0.445

High

1275373

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

3

High-throughput

0.445

High

1275381

SL9A6
Sodium/hydrogen exchanger 6

1

1

High-throughput

0.445

High

1275403

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

4

High-throughput

0.445

High

1275406

S12A9
Solute carrier family 12 member 9

1

4

High-throughput

0.445

High

1275407

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.445

High

1275411

ANKH
Mineralization regulator ANKH

1

1

High-throughput

0.445

High

106173

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

218379

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

385895

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.437

High

425552

ISG15
Ubiquitin-like protein ISG15

1

4

High-throughput

0.437

High

589017

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

695804

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768515

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

965053

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

1096732

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.437

High

1254397

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1275383

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

1275424

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

66385

T238L
Transmembrane protein 238-like

1

0

Small-scale

0.426

High

256066

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

1175871

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

0

High-throughput

0.426

High

1236199

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1275365

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.426

High

1275398

DIRC2
Solute carrier family 49 member 4

1

0

High-throughput

0.426

High

1275437

5MP1
eIF5-mimic protein 1

1

0

High-throughput

0.426

High

303244

S22A5
Organic cation/carnitine transporter 2

1

3

High-throughput

0.407

High

704031

5HT1E
5-hydroxytryptamine receptor 1E

1

1

High-throughput

0.407

High

727567

SC6A4
Sodium-dependent serotonin transporter

1

2

High-throughput

0.407

High

868058

OR1D4
Olfactory receptor 1D4

1

2

High-throughput

0.407

High

886085

CXCR3
C-X-C chemokine receptor type 3

1

6

High-throughput

0.407

High

1211923

S35F1
Solute carrier family 35 member F1

1

5

High-throughput

0.407

High

1275363

S22A9
Organic anion transporter 7

1

3

High-throughput

0.407

High

1275364

S15A3
Solute carrier family 15 member 3

1

3

High-throughput

0.407

High

1275369

ZNT7
Zinc transporter 7

1

4

High-throughput

0.407

High

1275400

S1PR3
Sphingosine 1-phosphate receptor 3

1

5

High-throughput

0.407

High

1275426

S23A1
Solute carrier family 23 member 1

1

1

High-throughput

0.407

High

906900

GPM6A
Neuronal membrane glycoprotein M6-a

3

0

High-throughput

0.347

High

488239

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

0

High-throughput

0.328

High

1198716

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.328

High

951939

SYCY2
Syncytin-2

2

0

High-throughput

0.316

High

1248603

LYPD5
Ly6/PLAUR domain-containing protein 5

2

0

High-throughput

0.316

High

1275376

MO2R1
Cell surface glycoprotein CD200 receptor 1

2

0

High-throughput

0.316

High

1275412

SPAG4
Sperm-associated antigen 4 protein

2

0

High-throughput

0.316

High

190559

COPT2
Protein SLC31A2

1

0

High-throughput

0.279

Low

191445

SIA8E
Alpha-2,8-sialyltransferase 8E

1

0

High-throughput

0.279

Low

762343

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.279

Low

838372

STA5A
Signal transducer and activator of transcription 5A

1

0

High-throughput

0.279

Low

916142

NAR1
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1

1

0

High-throughput

0.279

Low

1275362

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.279

Low

1275368

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1275396

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

1275397

SG3A1
Secretoglobin family 3A member 1

1

0

High-throughput

0.279

Low

1275404

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.279

Low

1275420

PCD10
Protocadherin-10

1

0

High-throughput

0.279

Low

1275422

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1275436

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.251

Low

248319

HBP1
HMG box-containing protein 1

1

0

High-throughput

0.249

Low

1275370

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1275377

MCLN3
Mucolipin-3

1

0

High-throughput

0.249

Low

1275415

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

1219500

ANR22
Ankyrin repeat domain-containing protein 22

1

0

High-throughput

0.232

Low

1275389

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low

1275413

S35C2
Solute carrier family 35 member C2

1

0

High-throughput

0.232

Low

1275432

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025