Protein: TFR2
Transferrin receptor protein 2 (TfR2)

Gene: TFR2
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q9UP52

Gene Ontology (top 5):
GO:0004998 - transferrin receptor activity
GO:0005886 - plasma membrane
GO:0006826 - iron ion transport
GO:0006879 - intracellular iron ion homeostasis
GO:0006898 - receptor-mediated endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

390970

TRFE
Serotransferrin

1

1

Small-scale

0.647

High

1180983

HFE
Hereditary hemochromatosis protein

1

3

Small-scale

0.618

High

1181292

LRRF1
Leucine-rich repeat flightless-interacting protein 1

2

1

High-throughput

0.611

High

1249457

OLFM4
Olfactomedin-4

2

0

High-throughput

0.580

High

1394468

SC22A
Vesicle-trafficking protein SEC22a

2

1

High-throughput

0.553

High

948963

CD81
CD81 antigen

1

7

Small-scale

0.552

High

260615

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.536

High

1370036

GSLG1
Golgi apparatus protein 1

1

1

High-throughput

0.536

High

1462434

TBD2B
TBC1 domain family member 2B

1

1

High-throughput

0.536

High

564565

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

284993

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

1

High-throughput

0.489

High

633943

ATP4A
Potassium-transporting ATPase alpha chain 1

1

1

Small-scale

0.479

High

155972

SOCS3
Suppressor of cytokine signaling 3

1

1

High-throughput

0.439

High

608951

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

1

High-throughput

0.437

High

1157396

EXT1
Exostosin-1

1

1

High-throughput

0.437

High

1412522

TINF2
TERF1-interacting nuclear factor 2

1

1

Small-scale

0.437

High

1438292

DEFM
Peptide deformylase, mitochondrial

1

1

High-throughput

0.437

High

1448327

FBX6
F-box only protein 6

1

3

High-throughput

0.437

High

1460248

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.437

High

1419332

TRI55
Tripartite motif-containing protein 55

1

4

High-throughput

0.417

High

1436049

DCR1B
5' exonuclease Apollo

1

0

Small-scale

0.297

High

342471

RPP29
Ribonuclease P protein subunit p29

1

0

High-throughput

0.279

Low

1312548

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

0

High-throughput

0.279

Low

688188

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025