HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: EPHA1 (P21709)
Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)
Gene: EPHA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 976
+	Hs
		348673 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EPHA7_HUMAN (2-975): 0: 1117: 43.22
+	Hs
		349222 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EPHA4_HUMAN (5-975): 0: 1108: 43.50
+	Hs
		1070202 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHA7_HUMAN (2-975): 0: 1117: 43.22
+	Hs
		349123 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EPHA1_HUMAN (1-976): 0: 1103: 100.00
+	Hs
		665604 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHB2_HUMAN (27-975): 0: 1112: 41.01
+	Hs
		348528 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EPHA3_HUMAN (22-975): 0: 1097: 43.01
+	Hs
		350187 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHA7_HUMAN (2-975): 0: 1117: 43.22
+	Hs
		349905 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHB2_HUMAN (27-975): 0: 1112: 41.01
+	Hs
		665398 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHA3_HUMAN (22-975): 0: 1097: 43.01
+	Hs
		665570 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		EPHB2_HUMAN (27-975): 0: 1112: 41.01
+	Hs
		350003 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHA4_HUMAN (5-975): 0: 1108: 43.50
+	Hs
		349904 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHA3_HUMAN (22-975): 0: 1097: 43.01
+	Hs
		349144 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EPHA2_HUMAN (24-976): 0: 1056: 49.90
+	Hs
		348527 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EPHA2_HUMAN (24-976): 0: 1056: 49.90
+	Hs
		665242 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHA2_HUMAN (24-976): 0: 1056: 49.90
+	Hs
		349903 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHA2_HUMAN (24-976): 0: 1056: 49.90
+	Hs
		665193 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		EPHA2_HUMAN (24-976): 0: 1056: 49.90
+	Hs
		872534 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHB4_HUMAN (13-975): 0: 1011: 40.31
+	Hs
		350002 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHB4_HUMAN (13-975): 0: 1011: 40.31
+	Hs
		349808 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		IGF1R_HUMAN (269-885): 5.75e-137: 446: 21.38