HitPredict

Interactor 1: FBLN4 (O95967)
EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1)
Gene: EFEMP2

Interactor 2: SGTB (Q96EQ0)
Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2)
Gene: SGTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.50	0.663

Property	Details
Experiments	29892012, 25416956, 16189514, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 304
+	Hs
		226650 FBLN4_HUMAN (1-443): 2.55e-70: 230: 100.00		SGTA_HUMAN (1-303): 1.75e-59: 194: 57.56
+	Hs
		3246 A0A0S2Z3V1_HUMAN (38-443): 2.51e-46: 166: 43.42		SGTA_HUMAN (1-303): 1.75e-59: 194: 57.56
+	Hs
		772293 FBN1_HUMAN (34-231): 8.33e-11: 66.6: 23.08		SGTB_HUMAN (1-304): 1.7e-67: 214: 100.00
+	Dm
		1475850 CUBN_DROME (4-238): 3.55e-29: 123: 17.77		Q9VH81_DROME (31-245): 6.94e-39: 144: 22.79
+	Hs
		226761 FBLN3_HUMAN (5-183): 6.22e-10: 62.9: 18.09		SGTA_HUMAN (1-303): 1.75e-59: 194: 57.56
+	Dm
		451871 NOTCH_DROME (128-410): 1.27e-18: 91: 16.39		Q9VH81_DROME (31-245): 6.94e-39: 144: 22.79
+	Dm
		451822 NOTCH_DROME (128-410): 1.27e-18: 91: 16.39		Q9V3E9_DROME (3-300): 3.58e-35: 134: 20.32
+	Dm
		1475802 TENA_DROME (3-172): 1.55e-11: 69.1: 10.05		Q9VH81_DROME (31-245): 6.94e-39: 144: 22.79
+	Dm
		1475746 Q9VTP0_DROME (4-118): 9.92e-11: 66.4: 14.29		Q9VH81_DROME (31-245): 6.94e-39: 144: 22.79
+	Dm
		262926 TENM_DROME (285-424): 3.57e-10: 64.4: 10.00		Q9V3E9_DROME (3-300): 3.58e-35: 134: 20.32