Interactor 1: INS (P01308)
Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Gene: INS
Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.55 | 0.458 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32457219 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001819 - positive regulation of cytokine production GO:0005158 - insulin receptor binding GO:0010629 - negative regulation of gene expression GO:0046628 - positive regulation of insulin receptor signaling pathway GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction and 1 others more... |
| Homologous interactions | 0 |
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Last updated: 15 Jul 2024
