HitPredict

Interactor 1: IGF2 (P01344)
Insulin-like growth factor II (IGF-II) (Somatomedin-A) (T3M-11-derived growth factor) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin]
Gene: IGF2

Interactor 2: IBP1 (P08833)
Insulin-like growth factor-binding protein 1 (IBP-1) (IGF-binding protein 1) (IGFBP-1) (Placental protein 12) (PP12)
Gene: IGFBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 10810289, 28514442, 33961781, 22578544
Identification Methods pull down, affinity chromatography technology, bio-layer interferometry, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IGFBP~Insulin, Insulin~Thyroglobulin_1
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0008286 - insulin receptor signaling pathway
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 180
Hs

1 259
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024