Protein: ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2)

Gene: ODP2, aceF
Organism: Escherichia coli K-12
Interactions: 83
UniProt ID: P06959

Gene Ontology (top 5):
GO:0004742 - dihydrolipoyllysine-residue acetyltransferase activity
GO:0005737 - cytoplasm
GO:0006086 - pyruvate decarboxylation to acetyl-CoA
GO:0006090 - pyruvate metabolic process
GO:0016407 - acetyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449830

DLDH
Dihydrolipoyl dehydrogenase

4

16

High-throughput

0.898

High

449848

ODP1
Pyruvate dehydrogenase E1 component

2

0

High-throughput

0.585

High

449825

UVRB
UvrABC system protein B

1

1

High-throughput

0.536

High

449827

EPMA
Elongation factor P--(R)-beta-lysine ligase

1

2

High-throughput

0.536

High

449843

CHEY
Chemotaxis protein CheY

1

1

High-throughput

0.536

High

449851

THIO2
Thioredoxin 2

1

4

High-throughput

0.536

High

449854

SELB
Selenocysteine-specific elongation factor

1

7

High-throughput

0.536

High

449856

RECQ
ATP-dependent DNA helicase RecQ

1

3

High-throughput

0.536

High

449859

MUKB
Chromosome partition protein MukB

1

5

High-throughput

0.536

High

449869

AIDB
Putative acyl-CoA dehydrogenase AidB

1

4

High-throughput

0.536

High

449887

FADJ
Fatty acid oxidation complex subunit alpha [Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase

1

2

High-throughput

0.536

High

361734

PHSM
Maltodextrin phosphorylase

1

0

High-throughput

0.513

High

365856

DPO1
DNA polymerase I

1

0

High-throughput

0.513

High

408517

3MG2
DNA-3-methyladenine glycosylase 2

1

0

High-throughput

0.513

High

449819

RL32
Large ribosomal subunit protein bL32

1

0

High-throughput

0.513

High

449820

RL34
Large ribosomal subunit protein bL34

1

0

High-throughput

0.513

High

449878

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

449879

RSMI
Ribosomal RNA small subunit methyltransferase I

1

0

High-throughput

0.513

High

449882

RL25
Large ribosomal subunit protein bL25

1

0

High-throughput

0.513

High

395134

UVRD
DNA helicase II

1

2

High-throughput

0.489

High

444266

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.489

High

449812

RECB
RecBCD enzyme subunit RecB

1

2

High-throughput

0.489

High

449813

T1RK
Type I restriction enzyme EcoKI endonuclease subunit

1

2

High-throughput

0.489

High

449834

RLUC
Ribosomal large subunit pseudouridine synthase C

1

6

High-throughput

0.489

High

449835

QMCA
Protein QmcA

1

3

High-throughput

0.489

High

449853

PAAJ
3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase

1

3

High-throughput

0.489

High

449855

TOP3
DNA topoisomerase 3

1

3

High-throughput

0.489

High

449861

RECG
ATP-dependent DNA helicase RecG

1

1

High-throughput

0.489

High

449867

INTA
Prophage integrase IntA

1

1

High-throughput

0.489

High

449870

ACNB
Aconitate hydratase B

1

1

High-throughput

0.489

High

449872

CSPB
Cold shock-like protein CspB

1

1

High-throughput

0.489

High

449873

HRPB
ATP-dependent RNA helicase HrpB

1

3

High-throughput

0.489

High

449874

INTS
Prophage integrase IntS

1

2

High-throughput

0.489

High

449875

HRPA
ATP-dependent RNA helicase HrpA

1

2

High-throughput

0.489

High

449876

YRAN
UPF0102 protein YraN

1

1

High-throughput

0.489

High

449884

BLUF
Blue light- and temperature-regulated antirepressor BluF

1

1

High-throughput

0.489

High

449815

ACP
Acyl carrier protein

1

1

High-throughput

0.484

High

449824

TGT
Queuine tRNA-ribosyltransferase

1

1

High-throughput

0.484

High

449832

ULAR
HTH-type transcriptional regulator UlaR

1

1

High-throughput

0.484

High

449845

GYRA
DNA gyrase subunit A

1

3

High-throughput

0.484

High

449850

PARC
DNA topoisomerase 4 subunit A

1

3

High-throughput

0.484

High

449821

RNH
Ribonuclease HI

1

0

High-throughput

0.464

High

449823

RPOA
DNA-directed RNA polymerase subunit alpha

1

0

High-throughput

0.464

High

449828

NAPD
Chaperone NapD

1

0

High-throughput

0.464

High

449846

NARJ
Nitrate reductase molybdenum cofactor assembly chaperone NarJ

1

0

High-throughput

0.464

High

449849

OGT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.464

High

449863

GLUQ
Glutamyl-Q tRNA(Asp) synthetase

1

2

High-throughput

0.457

High

449839

FIMB
Type 1 fimbriae regulatory protein FimB

1

2

High-throughput

0.442

High

449811

TYRR
HTH-type transcriptional regulatory protein TyrR

1

0

High-throughput

0.279

Low

449814

EX3
Exodeoxyribonuclease III

1

0

High-throughput

0.279

Low

449837

SDHA
Succinate dehydrogenase flavoprotein subunit

1

0

High-throughput

0.279

Low

449838

PDHR
Pyruvate dehydrogenase complex repressor

1

0

High-throughput

0.279

Low

449840

PINR
Serine recombinase PinR

1

0

High-throughput

0.279

Low

449844

DCM
DNA-cytosine methyltransferase

1

0

High-throughput

0.279

Low

449857

ICLR
Transcriptional repressor IclR

1

0

High-throughput

0.279

Low

449858

RECJ
Single-stranded-DNA-specific exonuclease RecJ

1

0

High-throughput

0.279

Low

449860

TRHO
tRNA uridine(34) hydroxylase

1

0

High-throughput

0.279

Low

449862

UBIC
Chorismate pyruvate-lyase

1

0

High-throughput

0.279

Low

449864

RNT
Ribonuclease T

1

0

High-throughput

0.279

Low

449865

3PASE
Inorganic triphosphatase

1

0

High-throughput

0.279

Low

449866

NNR
Bifunctional NAD(P)H-hydrate repair enzyme Nnr

1

0

High-throughput

0.279

Low

449868

FDHD
Sulfur carrier protein FdhD

1

0

High-throughput

0.279

Low

449871

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.279

Low

449877

UBIU
Ubiquinone biosynthesis protein UbiU

1

0

High-throughput

0.279

Low

449880

TADA
tRNA-specific adenosine deaminase

1

0

High-throughput

0.279

Low

449883

YBJX
Uncharacterized protein YbjX

1

0

High-throughput

0.279

Low

449885

PAAX
Transcriptional repressor PaaX

1

0

High-throughput

0.279

Low

449886

DGCM
Diguanylate cyclase DgcM

1

0

High-throughput

0.279

Low

432412

T1SK
Type I restriction enzyme EcoKI specificity subunit

1

0

High-throughput

0.261

Low

449816

END4
Endonuclease 4

1

0

High-throughput

0.253

Low

449817

RSMG
Ribosomal RNA small subunit methyltransferase G

1

0

High-throughput

0.253

Low

449818

PPK1
Polyphosphate kinase

1

0

High-throughput

0.253

Low

449822

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.253

Low

449826

YCIU
Putative double-stranded DNA mimic protein YciU

1

0

High-throughput

0.253

Low

449829

PHOL
PhoH-like protein

1

0

High-throughput

0.253

Low

449831

YBHF
Probable multidrug ABC transporter ATP-binding protein YbhF

1

0

High-throughput

0.253

Low

449833

ZNUC
Zinc import ATP-binding protein ZnuC

1

0

High-throughput

0.253

Low

449836

YBCJ
Putative RNA-binding protein YbcJ

1

0

High-throughput

0.253

Low

449841

YIBL
Uncharacterized protein YibL

1

0

High-throughput

0.253

Low

449842

CEDA
Cell division activator CedA

1

0

High-throughput

0.253

Low

449847

RRAB
Regulator of ribonuclease activity B

1

0

High-throughput

0.253

Low

449852

RLME
Ribosomal RNA large subunit methyltransferase E

1

0

High-throughput

0.253

Low

449881

NFI
Endonuclease V

1

0

High-throughput

0.253

Low


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Last updated: 11Aug2025