Interactor 1: APCL (O95996)
Adenomatous polyposis coli protein 2 (Adenomatous polyposis coli protein-like) (APC-like)
Gene: APC2
Interactor 2: AXIN2 (Q9Y2T1)
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin)
Gene: AXIN2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10021369 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arm~Axin_b-cat_bind, RGS~SAMP |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008013 - beta-catenin binding GO:0030877 - beta-catenin destruction complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 1 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Xl | |
|
|||||||||||
| + | Dm | |
 |
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Mm |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
