HitPredict

Interactor 1: DRB1 (P01911)
HLA class II histocompatibility antigen, DRB1 beta chain (Human leukocyte antigen DRB1) (HLA-DRB1)
Gene: HLA-DRB1

Interactor 2: ASIC4 (Q96FT7)
Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Amiloride-sensitive cation channel 4, pituitary)
Gene: ASIC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 266 Hs			1 539
+	Hs
		945213 DRB3_HUMAN (1-266): 1.45e-103: 303: 89.10		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		355051 DQB1_HUMAN (3-255): 2.06e-96: 285: 62.85		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		382497 HLAA_HUMAN (34-256): 9.63e-95: 284: 22.12		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		354532 HLAB_HUMAN (34-239): 8.44e-85: 259: 23.45		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		942290 DRB3_HUMAN (1-266): 1.45e-103: 303: 89.10		ASIC1_HUMAN (36-539): 0: 536: 48.95
+	Hs
		1278662 HMR1_HUMAN (38-258): 1.25e-73: 229: 25.45		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		1103656 HFE_HUMAN (58-237): 1.01e-11: 65.9: 27.03		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		382357 HLAA_HUMAN (34-256): 9.63e-95: 284: 22.12		SCNND_HUMAN (26-529): 1.36e-112: 354: 23.71
+	Hs
		354933 DRB1_HUMAN (1-266): 2.01e-107: 313: 100.00		SCNNA_HUMAN (5-156): 2.5e-30: 127: 20.00
+	Hs
		382585 DPB1_HUMAN (1-259): 1.5e-101: 298: 62.16		SCNNA_HUMAN (5-156): 2.5e-30: 127: 20.00
+	Hs
		354818 DQA1_HUMAN (126-246): 2.52e-12: 67: 27.48		SCNNA_HUMAN (5-156): 2.5e-30: 127: 20.00
+	Hs
		354680 DRA_HUMAN (117-217): 2.61e-10: 61.2: 30.69		SCNNA_HUMAN (5-156): 2.5e-30: 127: 20.00