HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: IMB5 (P53067)
Importin subunit beta-5 (114 kDa karyopherin) (Karyopherin subunit beta-5) (Karyopherin-114)
Gene: KAP114

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.965

Property	Details
Experiments	22562154, 16429126, 15679097, 11309407, 16554755, 37968396, 22199229
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Histone~IBN_N
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 1004
+	Hs
		312374 H2B1M_HUMAN (7-128): 9.18e-47: 148: 69.36		IPO7_HUMAN (1-1002): 0: 569: 13.62
+	Hs
		178138 H2B1D_HUMAN (7-128): 1.99e-45: 145: 70.16		IPO8_HUMAN (1-1002): 1.61e-179: 551: 12.55
+	Sc
		355946 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		IMB5_YEAST (1-1004): 2.34e-176: 542: 100.00
+	Hs
		178237 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		IPO8_HUMAN (1-1002): 1.61e-179: 551: 12.55
+	Hs
		617969 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		IPO9_HUMAN (3-1002): 1.48e-159: 499: 17.62
+	Hs
		1087348 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		IPO9_HUMAN (3-1002): 1.48e-159: 499: 17.62
+	Hs
		241614 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		IPO9_HUMAN (3-1002): 1.48e-159: 499: 17.62
+	Hs
		918619 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		IPO9_HUMAN (3-1002): 1.48e-159: 499: 17.62
+	Hs
		1231229 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		IPO9_HUMAN (3-1002): 1.48e-159: 499: 17.62
+	Hs
		1282947 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		IPO9_HUMAN (3-1002): 1.48e-159: 499: 17.62