HitPredict

Interactor 1: O97111 (O97111)
LD29223p (PAR-6) (Par-6, isoform B)
Gene: par-6

Interactor 2: L2GL (P08111)
Lethal(2) giant larvae protein
Gene: l(2)gl

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.727

Property	Details
Experiments	12629552, 22174071, 15177032, 18854163, 22036573, 38944040
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004860 - protein kinase inhibitor activity GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0045176 - apical protein localization GO:0045196 - establishment or maintenance of neuroblast polarity and 1 others more... GO:0055059 - asymmetric neuroblast division
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 351 Dm			1 1161
+	Hs
		1146340 PAR6B_HUMAN (13-336): 7.26e-69: 222: 48.01		L2GL1_HUMAN (1-1072): 0: 924: 35.10
+	Hs
		1146339 PAR6G_HUMAN (1-334): 5.9e-66: 214: 46.06		L2GL1_HUMAN (1-1072): 0: 924: 35.10
+	Mm
		1282963 PAR6A_MOUSE (10-264): 4.47e-59: 195: 53.49		L2GL1_MOUSE (1-1066): 0: 929: 35.92
+	Hs
		1241035 PAR6B_HUMAN (13-336): 7.26e-69: 222: 48.01		L2GL2_HUMAN (1-1055): 0: 898: 33.24
+	Hs
		1241034 PAR6G_HUMAN (1-334): 5.9e-66: 214: 46.06		L2GL2_HUMAN (1-1055): 0: 898: 33.24
+	Hs
		1146350 PAR6A_HUMAN (10-336): 1.63e-55: 186: 45.18		L2GL1_HUMAN (1-1072): 0: 924: 35.10
+	Hs
		1241043 PAR6A_HUMAN (10-336): 1.63e-55: 186: 45.18		L2GL2_HUMAN (1-1055): 0: 898: 33.24
+	Ce
		112534 PAR6_CAEEL (18-319): 2.76e-58: 192: 50.00		G5EEI1_CAEEL (1-962): 0: 599: 19.19