Interactor 1: P53 (P02340)
Cellular tumor antigen p53 (Tumor suppressor p53)
Gene: Tp53

Interactor 2: MELK (Q61846)
Maternal embryonic leucine zipper kinase (EC 2.7.11.1) (Protein kinase PK38) (mPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)
Gene: MELK

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 0.60 0.578

The method score is based on:

Property Details
Experiments 22532570
Identification Methods pull down, affinity chromatography technology, enzymatic study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0008283 - cell population proliferation
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 390
Mm

1 643
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024