Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 26456826, 25237190, 7681433, 19738201, 22451694
Identification Methods pull down, affinity chromatography technology, surface plasmon resonance, cross-linking study, enzyme linked immunosorbent assay
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Integrin_beta~fn3
Common GO terms GO:0002020 - protease binding
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007160 - cell-matrix adhesion
and 4 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 2477
Hs

1 798
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Last updated: 15 Jul 2024