HitPredict

Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 19738201
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen GO:0062023 - collagen-containing extracellular matrix GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2477 Hs			1 135
+	Hs
		362790 FINC_HUMAN (1-2477): 0: 1538: 100.00		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		362931 FINC_HUMAN (1-2477): 0: 1538: 100.00		LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58
+	Hs
		121070 FINC_HUMAN (1-2477): 0: 1538: 100.00		LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13
+	Hs
		119068 FINC_HUMAN (1-2477): 0: 1538: 100.00		LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50
+	Hs
		449281 SDK2_HUMAN (1428-2469): 8.32e-95: 345: 10.88		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		572370 SDK2_HUMAN (1428-2469): 8.32e-95: 345: 10.88		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		814965 SDK2_HUMAN (1428-2469): 8.32e-95: 345: 10.88		LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58
+	Hs
		449191 PTPRB_HUMAN (574-1553): 1.99e-62: 239: 15.64		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		449306 SDK1_HUMAN (1720-2405): 2.22e-31: 137: 8.25		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		572394 SDK1_HUMAN (1720-2405): 2.22e-31: 137: 8.25		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		814978 SDK1_HUMAN (1720-2405): 2.22e-31: 137: 8.25		LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58
+	Hs
		121183 SDK1_HUMAN (1720-2405): 2.22e-31: 137: 8.25		LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13
+	Hs
		449192 PTPRD_HUMAN (1998-2416): 1.38e-17: 92.5: 9.47		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		439224 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		540411 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		121099 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13
+	Hs
		1253493 TENR_HUMAN (207-352): 4.02e-10: 67.6: 14.97		PPL13_HUMAN (1-132): 2.72e-43: 140: 18.57
+	Hs
		50511 A1L306_HUMAN (207-352): 6.04e-10: 67.2: 14.97		PPL13_HUMAN (1-132): 2.72e-43: 140: 18.57