Protein: EPHB1
Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)

Gene: EPHB1
Organism: Homo sapiens
Interactions: 28
UniProt ID: P54762

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001771 - immunological synapse formation
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005524 - ATP binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

651239

CBL
E3 ubiquitin-protein ligase CBL

2

20

Small-scale

0.806

High

461310

HS90A
Heat shock protein HSP 90-alpha

2

20

Small-scale

0.754

High

593950

NCK1
SH2/SH3 adapter protein NCK1

1

20

Small-scale

0.751

High

932029

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.751

High

932031

GRB10
Growth factor receptor-bound protein 10

1

20

Small-scale

0.751

High

932033

GRB7
Growth factor receptor-bound protein 7

1

20

Small-scale

0.740

High

62106

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

12

High-throughput

0.726

High

424649

KPCG
Protein kinase C gamma type

1

19

Small-scale

0.647

High

914526

EFNA5
Ephrin-A5

1

20

Small-scale

0.647

High

710798

EPHB2
Ephrin type-B receptor 2

1

19

High-throughput

0.646

High

931920

EPHB4
Ephrin type-B receptor 4

1

19

High-throughput

0.646

High

410735

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

162812

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

20

Small-scale

0.618

High

468217

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

932034

CDC37
Hsp90 co-chaperone Cdc37

1

19

Small-scale

0.618

High

932035

SPSB4
SPRY domain-containing SOCS box protein 4

2

13

High-throughput

0.601

High

666083

PPAC
Low molecular weight phosphotyrosine protein phosphatase

1

3

Small-scale

0.561

High

932030

MALL
MAL-like protein

1

3

High-throughput

0.536

High

464685

CXB1
Gap junction beta-1 protein

1

13

Small-scale

0.512

High

932028

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

11

Small-scale

0.479

High

254906

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

12

High-throughput

0.445

High

844743

EAA1
Excitatory amino acid transporter 1

1

14

High-throughput

0.445

High

932032

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

10

High-throughput

0.445

High

932036

SPSB2
SPRY domain-containing SOCS box protein 2

1

13

High-throughput

0.445

High

932037

SC6A7
Sodium-dependent proline transporter

1

7

High-throughput

0.445

High

932038

S40A1
Ferroportin

1

1

High-throughput

0.445

High

612949

EGR1
Early growth response protein 1

1

8

High-throughput

0.437

High

932039

DNM3B
DNA

1

1

Small-scale

0.437

High


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Last updated: 11Aug2025