Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: CAV2 (P51636)
Caveolin-2
Gene: CAV2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.86 | 0.60 | 0.719 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15273741, 25402006, 24658140, 16799092, unassigned2173 |
| Identification Methods | pull down, two hybrid, protein complementation assay, affinity chromatography technology, anti bait coimmunoprecipitation, ubiquitin reconstruction |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000139 - Golgi membrane GO:0005634 - nucleus GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0005925 - focal adhesion and 4 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
