Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10781609, 15273741, 34079125, 12388423, 25402006, 24658140, 12354760, 9374534, 35614042, 16407214, 19446582, 16799092, 22411794, unassigned2173, 15657067 |
| Identification Methods | affinity chromatography technology, pull down, proximity labelling technology, two hybrid, protein complementation assay, anti bait coimmunoprecipitation, ubiquitin reconstruction |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000139 - Golgi membrane GO:0005768 - endosome GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane and 11 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
