Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 11493006, 19738201
Identification Methods pull down, affinity chromatography technology, cross-linking study
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~fn1, I-set~fn3, Ig_3~fn3, Laminin_EGF~fn3
Common GO terms GO:0001525 - angiogenesis
GO:0005576 - extracellular region
GO:0005604 - basement membrane
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2477
Hs

1 4391
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Last updated: 15 Jul 2024